Endocrine Abstracts

Introduction: Overt hypothyroidism and severe subclinical hypothyroidism (ScH) are associated with dyslipidaemia, and its condition is reversible after thyroid replacement therapy. We investigated the effect of levothyroxine therapy on lipid parameters in patients with mild form of subclinical hypothyroidism (ScH).Material and methods: Fifty-seven patients with newly diagnosed ScH with TSH levels below 10 mU/l and 30 age and sex-matched healthy subjects ...

Introduction: Hyponatraemia is the commonest electrolyte disorder in clinical practice and is closely associated with increased morbidity, mortality and length of hospital stay. It can be classified into mild (124–134 mmol/l), moderate (115–124 mmol/l), and severe (<115 mmol/l). The aim of the study was to determine the prevalence, aetiology, and management of hyponatraemia in general hospital.Methods: A total of 4139 acute medical admissio...

Introduction: The aim of this study was to compare prolactin receptor gene (Prlr) expression in the duodenum, vertebra and kidney, during physiological and medicamentous hyperprolactinaemia.Methods: Wistar female rats 18 weeks old were divided into: Group P: nine rats, 3 week pregnant; Group M: ten rats that were intramuscular administrated Sulpirid (10 mg/kg) twice daily for 3 weeks; and age matched nulliparous rats as a control group: ten rats...

Introduction: Autoimmune thyroid diseases, including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), are complex diseases combining genetic susceptibility and environmental encounters leading to the breakdown of immune tolerance. The relationship between thyroid cancer (TC) and HT has been proven (Guarino et al. 2010), and the antibody specific association has been demonstrated (Azizi et al. 2014). Overexpression of claudin-1 appears to be an...

Aim: The aim of the study is to identify the current level of knowledge of nursing students at the end of their studies in the Master’s degree about competence in general nursing, work accidents and competence of endocrine nurses in diabetes care.Methods: We had 673 nursing students enrolled in the study. They were all students at the end of their study in the master’s degree. 76% of the students were practicing nurses with more than 3 years of...

Gender dysphoria (GD) leading to hormonal treatment and sex reassignment surgery that spans two generations has not been reported so far.The mother was diagnosed with GD at the age of 47. As an only child she suffered from emotional, physical, and sexual abuse by her parents. From the age of 3, she fantasized being a boy and started behaving like one. During later youth the genderdysphoric feelings were repressed. She married at the age of 18. One year l...

Background and aim: We carried out a prospective 1-year study to examine the association of sudomotor dysfunction with mortality in patients with chronic kidney disease.Materials and methods: 97 patients from dialysis unit (28 with diabetic nephropathy (DN); 37 with nephroangiosclerosis, (NA), 18 with glomerulonephritis (GN), 14 with other conditions (O)); 32 with type 2 DM and creatinine clearance (CrCl) 30–50 ml/min; and 24 transplanted patients w...

Background: Constant feedback is required for optimal performance, allowing for flexible planning of outpatient diabetes schools.Aim: To study patient satisfaction with the results of education in the outpatient school for type 1 diabetes (s.d.).Materials and methods: 96 patients with type 1 diabetes (T1D) were included. The survey contained 5 questions: Have patients previously been trained at the s.d.? Which sou...

Subclinical hyperthyroidism (ScHyper) is a condition with suppressed TSH, and normal free T3 and free T4 hormones, affecting 10% of the population. There are two subgroups of patients, the first group with TSH lower than 0.1 U/l, and the second group with mildly suppressed TSH between 0.1 and the lower assay reference limit. The patients from the first group should be treated, but there is no evidence for therapy for the second group of patients.We prese...

Introduction: Parathyroid gland proliferative disorders include adenoma, hyperplasia and carcinoma. Adenoma and hyperplasia are found more commonly in women, while carcinoma, which is very rare, is found in both sexes equally. The aim of this study was to investigate parathyroid gland tumors surgically removed at University Hospital Centre Osijek between 2016 and 2019. Also to review tumor location, size and histopathology and compare sex difference.Pati...